On January 12, 2018, Advaita released a major updates to its platform, with improvements to iPathwayGuide, iVariantGuide, and iBioguide.
The Advaita Knowledgebase was updated to version 1711 and now includes:
Uploading and analyzing data is easy. Here is a quick video tutorial explaining how.
1. SELECT/ UPLOAD FILE
The first step is to upload your VCF file containing all of the variants and samples you want to analyze. Here are a few tips:
Once uploaded, select the checkbox next to the file you’d like to analyze. You will then be prompted to verify the reference assembly and select the type of analysis you wish to perform, including:
Lastly, iVariantGuide allows you to pre-filter your variants by quality, read depth, and FILTER flags. If there are certain quality control measures you know you’ll apply anyway, this step will help to focus the variants in your analysis to only those you are confident of, while ensuring a more favorable browsing experience.
2. ADD SAMPLES TO GROUPS
You may assign information to each sample in the file (sex, group, parents) in the page or by uploading a file containing the necessary information. You may also re-name samples (in case the VCF sample names are not easy to read). iVariantGuide accepts two formats for sample information: ped for pedigree analysis and txt for group vs group and tumor/ normal analyses. For a description and example of each file format, see below.
File Formats for Specifying Sample Info
IMPORTANT NOTE: Check the order of your samples! The first sample in the PED file is always the proband, and the first phenotype found is Affected. The second phenotype found (the first row with a phenotype different from that of the proband) is Unaffected, and the third is Unknown. For TXT files, the first group found is Tumor/ Case and the second is Normal/ Control.
3. CREATE REPORT
On the last page you can review the selections you made so far, and give your analysis a Title and Description. Once satisfied, click submit. Each dataset takes about 15 minutes to analyze. You will get an automated email as soon as your analysis is complete.
With Advaita's latest update to its applications and knowledge base, Advaita updated its API for iVariantGuide and iPathwayGuide.
An API or (Application Program Interface) is a set of routines, protocols, and tools for building software applications. An API specifies how software components should interact. Advaita's API is designed
On February 27, 2017, Advaita released a major updates to its platform. These are the release notes.
IMPROVEMENTS TO: iPathwayGuide, iVariantGuide, iBioguide, and the Advaita Knowledge Base
IMPROVEMENTS TO iPATHWAYGUIDE
The Commercial Release of iVairantGuide is here! With this commercial release we now have the following enhancements from the last Beta:
In the pre-commercial release of iVariantGuide the following issues have been addressed: